Varaico: Literature-Extracted Genetic Variants

Gene:IRS1
Variant:p.G1158E
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IRS1

NM_005544.3:p.G1158E

Associated Papers

Association study of IRS1 gene polymorphisms with type 2 diabetes in south Indians.

Bodhini D et al.

Diabetes Technology & Therapeutics, 2011

Human insulin receptor substrate-1 (IRS-1) polymorphism G972R causes IRS-1 to associate with the insulin receptor and inhibit receptor autophosphorylation.

McGettrick AJ et al.

The Journal of Biological Chemistry, 2005

Genetic variants of insulin receptor substrate-1 (IRS-1) in syndromes of severe insulin resistance. Functional analysis of Ala513Pro and Gly1158Glu IRS-1.

Berger D et al.

Diabetic Medicine : a Journal of the British Diabetic Association, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."