Varaico: Literature-Extracted Genetic Variants

Gene:IRS1
Variant:p.G819R
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IRS1

NM_005544.3:p.G819R

Associated Papers

A rare co-segregation-mutation in the insulin receptor substrate 1 gene in one Chinese family with ankylosing spondylitis.

Rong J et al.

Plos One, 2015

Molecular scanning for mutations in the insulin receptor substrate-1 (IRS-1) gene in Turkish with type 2 diabetes mellitus.

Orkunoglu Suer FE et al.

Endocrine Journal, 2005

Human insulin receptor substrate-1 (IRS-1) polymorphism G972R causes IRS-1 to associate with the insulin receptor and inhibit receptor autophosphorylation.

McGettrick AJ et al.

The Journal of Biological Chemistry, 2005

A study to survey susceptible genetic factors responsible for troglitazone-associated hepatotoxicity in Japanese patients with type 2 diabetes mellitus.

Watanabe I et al.

Clinical Pharmacology and Therapeutics, 2003

Genetic variants of insulin receptor substrate-1 (IRS-1) in syndromes of severe insulin resistance. Functional analysis of Ala513Pro and Gly1158Glu IRS-1.

Berger D et al.

Diabetic Medicine : a Journal of the British Diabetic Association, 2002

Expression of variant forms of insulin receptor substrate-1 identified in patients with noninsulin-dependent diabetes mellitus.

Imai Y et al.

The Journal of Clinical Endocrinology and Metabolism, 1997

Molecular scanning for mutations in the insulin receptor substrate-1 (IRS-1) gene in Mexican Americans with Type 2 diabetes mellitus.

Celi FS et al.

Diabetes/metabolism Research and Reviews, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."