Associated Papers
IRS1 gene polymorphisms Gly972Arg and Ala513Pro are not associated with insulin resistance and type 2 diabetes risk in non-obese Turkish population.
Arikoglu H et al.
Meta Gene, 2014
Genetic variants of the insulin receptor substrate-1 are influencing the therapeutic efficacy of oral antidiabetics.
Seeringer A et al.
Diabetes, Obesity & Metabolism, 2010
Study of association of IRS-1 and IRS-2 genes polymorphisms with clinical and metabolic features in women with polycystic ovary syndrome. Is there an impact?
Christopoulos P et al.
Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology, 2010
Abnormal glucose tolerance and insulin resistance in polycystic ovary syndrome amongst the Taiwanese population- not correlated with insulin receptor substrate-1 Gly972Arg/Ala513Pro polymorphism.
Lin TC et al.
Bmc Medical Genetics, 2006
Molecular scanning for mutations in the insulin receptor substrate-1 (IRS-1) gene in Turkish with type 2 diabetes mellitus.
Orkunoglu Suer FE et al.
Endocrine Journal, 2005
Human insulin receptor substrate-1 (IRS-1) polymorphism G972R causes IRS-1 to associate with the insulin receptor and inhibit receptor autophosphorylation.
McGettrick AJ et al.
The Journal of Biological Chemistry, 2005
A study to survey susceptible genetic factors responsible for troglitazone-associated hepatotoxicity in Japanese patients with type 2 diabetes mellitus.
Watanabe I et al.
Clinical Pharmacology and Therapeutics, 2003
Impact of natural IRS-1 mutations on insulin signals: mutations of IRS-1 in the PTB domain and near SH2 protein binding sites result in impaired function at different steps of IRS-1 signaling.
Yoshimura R et al.
Diabetes, 1997
Molecular scanning for mutations in the insulin receptor substrate-1 (IRS-1) gene in Mexican Americans with Type 2 diabetes mellitus.
Celi FS et al.
Diabetes/metabolism Research and Reviews, 0
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