Varaico: Literature-Extracted Genetic Variants

Gene:ITGA2
Variant:p.E534K
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ITGA2

NM_002203.4:p.E534K

Associated Papers

Immunogenetic polymorphism of human platelet antigens in the Saudi population: Insights into genetic diversity and alloimmune risk.

AlSuhaibani O et al.

Vox Sanguinis, 2025

The Genetic Basis of Strokes in Pediatric Populations and Insight into New Therapeutic Options.

Jankovic M et al.

International Journal of Molecular Sciences, 2022

Mechanisms of thrombocytopenia in platelet-type von Willebrand disease.

Bury L et al.

Haematologica, 2019

30655369 (PubMed )
Supplement: 2018.200378.BURY_SUPPL.pdf

Recent advances in understanding the clinical relevance of antiplatelet alloantibodies.

Guz K et al.

Polish Archives of Internal Medicine, 2017

Comparison of a simple-probe real-time PCR and multiplex PCR techniques for HPA-1 to HPA-6 and HPA-15 genotyping.

Kengkate M et al.

Journal of Clinical Laboratory Analysis, 2015

The eSNV-detect: a computational system to identify expressed single nucleotide variants from transcriptome sequencing data.

Tang X et al.

Nucleic Acids Research, 2014

25352556 (PubMed )
Supplement: supp_gku1005_nar-01266-met-n-2014-File012.xlsx › TCGA-A7-A0CG-01A.domain

HPA-5 typing discrepancy reveals an Ile503Leu substitution in platelet GPIa (α2 integrin).

Bertrand G et al.

Vox Sanguinis, 2013

Platelet adhesion to decorin but not collagen I correlates with the integrin α2 dimorphism E534K, the basis of the human platelet alloantigen (HPA)-5 system.

Kunicki TJ et al.

Haematologica, 2012

Integrin genes and susceptibility to human melanoma.

Lenci RE et al.

Mutagenesis, 2012

Frequency of human platelet antigens in oncohematological patients with thrombocytopenia and the probability of incompatibility to platelet transfusions.

Bianchi JV et al.

Revista Brasileira De Hematologia E Hemoterapia, 2012

A new platelet alloantigen, Swi(a) , located on glycoprotein Ia identified in a family with fetal and neonatal alloimmune thrombocytopenia.

Kroll H et al.

Transfusion, 2011

Simultaneous genotyping of human platelet antigen-1 to 17w by polymerase chain reaction sequence-based typing.

Xu X et al.

Vox Sanguinis, 2009

The new platelet alloantigen Cab a: a single point mutation Gln 716 His on the alpha 2 integrin.

Bertrand G et al.

Transfusion, 2009

Integrin alpha-2 and beta-3 gene polymorphisms and colorectal cancer risk.

Gerger A et al.

International Journal of Colorectal Disease, 2009

Polymorphisms in predicted microRNA-binding sites in integrin genes and breast cancer: ITGB4 as prognostic marker.

Brendle A et al.

Carcinogenesis, 2008

Association of integrin alpha2 gene variants with ischemic stroke.

Matarin M et al.

Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism, 2008

Integrin alpha-2 and beta-3 gene polymorphisms and breast cancer risk.

Langsenlehner U et al.

Breast Cancer Research and Treatment, 2006

Molecular typing of human platelet antigens in immune thrombocytopenia patients in northern Brazil.

Carmo JCD et al.

Revista Brasileira De Hematologia E Hemoterapia, 0

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