Varaico: Literature-Extracted Genetic Variants

Gene:ITGA2
Variant:p.E550K
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ITGA2

NM_002203.4:p.E550K

Associated Papers

Frequency of Human Platelet Antigens -1 to -5 and -15 in Turkmen Blood Donors.

Nozarimirarkolaei M et al.

Advanced Biomedical Research, 2023

Association of the human platelet antigens polymorphisms with platelet count in patients with COVID-19.

Ghaffari K et al.

Frontiers in Medicine, 2023

Association of human platelet alloantigens encoding gene polymorphisms with the risk of Coronary artery disease in Iranian patients.

Malakootikhah F et al.

Bmc Cardiovascular Disorders, 2021

Genetic determinants of platelet reactivity during acetylsalicylic acid therapy in diabetic patients: evaluation of 27 polymorphisms within candidate genes.

Postula M et al.

Journal of Thrombosis and Haemostasis : Jth, 2011

Single nucleotide polymorphisms of integrin alpha-2 and beta-3 genes are not associated with relapse-free and overall survival in colorectal cancer patients.

Hofmann G et al.

Anticancer Research, 2011

Analysis of common germline polymorphisms as prognostic factors in patients with lymph node-positive breast cancer.

Knechtel G et al.

Journal of Cancer Research and Clinical Oncology, 2010

Enhanced binding of poly(ADP-ribose)polymerase-1 and Ku80/70 to the ITGA2 promoter via an extended cytosine-adenosine repeat.

Cheli Y et al.

Plos One, 2010

Human platelet alloantigens (HPA) 1, HPA2, HPA3, HPA4, and HPA5 polymorphisms in sickle cell anemia patients with vaso-occlusive crisis.

Al-Subaie AM et al.

European Journal of Haematology, 2009

Integrin alpha-2 and beta-3 gene polymorphisms and colorectal cancer risk.

Gerger A et al.

International Journal of Colorectal Disease, 2009

Polymorphisms of the human platelet alloantigens HPA-1, HPA-2, HPA-3, and HPA-4 in ischemic stroke.

Saidi S et al.

American Journal of Hematology, 2008

Association of human platelet alloantigen 1 through 5 polymorphisms with ischemic stroke.

Saidi S et al.

Cerebrovascular Diseases (basel, Switzerland), 2008

A multigenic approach to predict breast cancer risk.

Gerger A et al.

Breast Cancer Research and Treatment, 2007

Genetic polymorphisms of platelet glycoprotein Ia and the risk for premature myocardial infarction: effects on the release of sCD40L during the acute phase of premature myocardial infarction.

Antoniades C et al.

Journal of the American College of Cardiology, 2006

Integrin alpha-2 and beta-3 gene polymorphisms and breast cancer risk.

Langsenlehner U et al.

Breast Cancer Research and Treatment, 2006

Genetic polymorphisms of platelet adhesive molecules: association with breast cancer risk and clinical presentation.

Ayala F et al.

Breast Cancer Research and Treatment, 2003

Iron deficiency anaemia in young women.

Carlsson LE et al.

European Journal of Haematology, 2002

Platelet glycoprotein gene polymorphisms and risk of thrombosis: facts and fancies.

Reiner AP et al.

Reviews in Clinical and Experimental Hematology, 2001

A point mutation Thr(799)Met on the alpha(2) integrin leads to the formation of new human platelet alloantigen Sit(a) and affects collagen-induced aggregation.

Santoso S et al.

Blood, 1999

Analysis of platelet glycoprotein Ia (alpha2 integrin) allele frequencies in three North American populations reveals genetic association between nucleotide 807C/T and amino acid 505 Glu/Lys (HPA-5) dimorphisms.

Reiner AP et al.

Thrombosis and Haemostasis, 1998

Platelet GP IIIA polymorphism HPA-1 (PLA1/2) is associated with hypertension as the primary cause for end-stage renal disease in hemodialysis patients from Greece.

Chiras T et al.

In Vivo (athens, Greece), 0

Genetic aspects of ischemic stroke: coagulation, homocysteine, and lipoprotein metabolism as potential risk factors.

Stankovic S et al.

Critical Reviews in Clinical Laboratory Sciences, 0

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