Varaico: Literature-Extracted Genetic Variants

Gene:ITGAM
Variant:p.A858V
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ITGAM

NM_000632.4:p.A858V

Associated Papers

Clinical features and expression of type I interferon-inducible genes in systemic lupus erythematosus patients harboring rs1143679 polymorphism in China: a single-center, retrospective study.

Xu W et al.

Clinical Rheumatology, 2021

β2 Integrins-Multi-Functional Leukocyte Receptors in Health and Disease.

Bednarczyk M et al.

International Journal of Molecular Sciences, 2020

ITGAM is a risk factor to systemic lupus erythematosus and possibly a protection factor to rheumatoid arthritis in patients from Mexico.

Ramírez-Bello J et al.

Plos One, 2019

CD11b Activity Modulates Pathogenesis of Lupus Nephritis.

Khan SQ et al.

Frontiers in Medicine, 2018

Updates in Lupus Genetics.

Deng Y et al.

Current Rheumatology Reports, 2017

CD11b activation suppresses TLR-dependent inflammation and autoimmunity in systemic lupus erythematosus.

Faridi MH et al.

The Journal of Clinical Investigation, 2017

The Systemic Lupus Erythematosus-Associated Single Nucleotide Polymorphism rs1143678 in Integrin αM Cytoplasmic Tail Generates a 14-3-3ζ Binding Site That Is Proinflammatory.

Ong LT et al.

Journal of Immunology (baltimore, Md. : 1950), 2017

The genetic basis of systemic lupus erythematosus: What are the risk factors and what have we learned.

Teruel M et al.

Journal of Autoimmunity, 2016

Genetics of Lupus Nephritis: Clinical Implications.

Munroe ME et al.

Seminars in Nephrology, 2015

Resequencing the susceptibility gene, ITGAM, identifies two functionally deleterious rare variants in systemic lupus erythematosus cases.

Roberts AL et al.

Arthritis Research & Therapy, 2014

Multiple lupus-associated ITGAM variants alter Mac-1 functions on neutrophils.

Zhou Y et al.

Arthritis and Rheumatism, 2013

Integrin genes and susceptibility to human melanoma.

Lenci RE et al.

Mutagenesis, 2012

ITGAM Arg77His is associated with disease susceptibility, arthritis, and renal symptoms in systemic lupus erythematosus patients from a sample of the Polish population.

Warchoł T et al.

Dna and Cell Biology, 2011

The landscape of human genes involved in the immune response to parasitic worms.

Fumagalli M et al.

Bmc Evolutionary Biology, 2010

ITGAM is associated with disease susceptibility and renal nephritis of systemic lupus erythematosus in Hong Kong Chinese and Thai.

Yang W et al.

Human Molecular Genetics, 2009

Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.

Hom G et al.

The New England Journal of Medicine, 2008

Evaluation of resequencing on number of tag SNPs of 13 atherosclerosis-related genes in Thai population.

Tocharoentanaphol C et al.

Journal of Human Genetics, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."