Varaico: Literature-Extracted Genetic Variants

Gene:ITGAM
Variant:p.P1146S
Back to variants list

ITGAM

NM_000632.4:p.P1146S

Associated Papers

Loss of CD11b Accelerates Lupus Nephritis in Lyn-Deficient Mice Without Disrupting Glomerular Leukocyte Trafficking.

Gottschalk TA et al.

Frontiers in Immunology, 2022

Clinical features and expression of type I interferon-inducible genes in systemic lupus erythematosus patients harboring rs1143679 polymorphism in China: a single-center, retrospective study.

Xu W et al.

Clinical Rheumatology, 2021

MiR-21 binding site SNP within ITGAM associated with psoriasis susceptibility in women.

Hruska P et al.

Plos One, 2019

CD11b Activity Modulates Pathogenesis of Lupus Nephritis.

Khan SQ et al.

Frontiers in Medicine, 2018

Updates in Lupus Genetics.

Deng Y et al.

Current Rheumatology Reports, 2017

CD11b activation suppresses TLR-dependent inflammation and autoimmunity in systemic lupus erythematosus.

Faridi MH et al.

The Journal of Clinical Investigation, 2017

The Systemic Lupus Erythematosus-Associated Single Nucleotide Polymorphism rs1143678 in Integrin αM Cytoplasmic Tail Generates a 14-3-3ζ Binding Site That Is Proinflammatory.

Ong LT et al.

Journal of Immunology (baltimore, Md. : 1950), 2017

Genetic Variation in Pattern Recognition Receptors and Adaptor Proteins Associated With Development of Chronic Q Fever.

Schoffelen T et al.

The Journal of Infectious Diseases, 2015

Genetics of Lupus Nephritis: Clinical Implications.

Munroe ME et al.

Seminars in Nephrology, 2015

Resequencing the susceptibility gene, ITGAM, identifies two functionally deleterious rare variants in systemic lupus erythematosus cases.

Roberts AL et al.

Arthritis Research & Therapy, 2014

Multiple lupus-associated ITGAM variants alter Mac-1 functions on neutrophils.

Zhou Y et al.

Arthritis and Rheumatism, 2013

Integrin genes and susceptibility to human melanoma.

Lenci RE et al.

Mutagenesis, 2012

ITGAM is associated with disease susceptibility and renal nephritis of systemic lupus erythematosus in Hong Kong Chinese and Thai.

Yang W et al.

Human Molecular Genetics, 2009

Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.

Hom G et al.

The New England Journal of Medicine, 2008

Evaluation of resequencing on number of tag SNPs of 13 atherosclerosis-related genes in Thai population.

Tocharoentanaphol C et al.

Journal of Human Genetics, 2008

[Phenotyping and genotyping in patients with inflammatory bowel disease in a reference center in Colombia].

Parra Izquierdo V et al.

Revista De Gastroenterologia Del Peru : Organo Oficial De La Sociedad De Gastroenterologia Del Peru, 0

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."