Varaico: Literature-Extracted Genetic Variants

Gene:ITGB2
Variant:p.F299C
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ITGB2

NM_000211.5:p.F299C

Associated Papers

Small molecule integrin antagonists that bind to the beta2 subunit I-like domain and activate signals in one direction and block them in the other.

Shimaoka M et al.

Immunity, 2003

Structures of the alpha L I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation.

Shimaoka M et al.

Cell, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."