Varaico: Literature-Extracted Genetic Variants

Gene:ITGB2
Variant:p.S136A
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ITGB2

NM_000211.5:p.S136A

Associated Papers

Structure-function of the putative I-domain within the integrin beta 2 subunit.

Xiong YM et al.

The Journal of Biological Chemistry, 2001

A novel leukocyte adhesion deficiency caused by expressed but nonfunctional beta2 integrins Mac-1 and LFA-1.

Hogg N et al.

The Journal of Clinical Investigation, 1999

Overlapping, but not identical, sites are involved in the recognition of C3bi, neutrophil inhibitory factor, and adhesive ligands by the alphaMbeta2 integrin.

Zhang L et al.

The Journal of Biological Chemistry, 1996

Beta 2 (CD18) mutations abolish ligand recognition by I domain integrins LFA-1 (alpha L beta 2, CD11a/CD18) and MAC-1 (alpha M beta 2, CD11b/CD18).

Bajt ML et al.

The Journal of Biological Chemistry, 1995

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."