Varaico: Literature-Extracted Genetic Variants

Gene:ITK
Variant:p.R265K
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ITK

NM_005546.4:p.R265K

Associated Papers

Kinome-wide decoding of network-attacking mutations rewiring cancer signaling.

Creixell P et al.

Cell, 2015

26388441 (PubMed )
Supplement: mmc8.xlsx › COSMIC_v67MappedToEnsembl_right

The linker between SH2 and kinase domains positively regulates catalysis of the Tec family kinases.

Joseph RE et al.

Biochemistry, 2007

A remote substrate docking mechanism for the tec family tyrosine kinases.

Joseph RE et al.

Biochemistry, 2007

Inducible T cell tyrosine kinase (ITK): structural requirements and actin polymerization.

Tsoukas CD et al.

Advances in Experimental Medicine and Biology, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."