Associated Papers
Accurate affinity models for SH2 domains from peptide binding assays and free-energy regression.
Gagoski D et al.
Protein Science : a Publication of the Protein Society, 2025
Accurate sequence-to-affinity models for SH2 domains from multi-round peptide binding assays coupled with free-energy regression.
Gagoski D et al.
Biorxiv : the Preprint Server for Biology, 2025
Multiple Tumors in a Patient with Interleukin-2-Inducible T-Cell Kinase Deficiency: A Case Report.
Di Filippo M et al.
International Journal of Molecular Sciences, 2024
Inherited rare variants in homologous recombination and neurodevelopmental genes are associated with increased risk of neuroblastoma.
Bonfiglio F et al.
Ebiomedicine, 2023
Role of the IL-2 inducible tyrosine kinase ITK and its inhibitors in disease pathogenesis.
Lechner KS et al.
Journal of Molecular Medicine (berlin, Germany), 2020
Analysis of the FLVR motif of SHIP1 and its importance for the protein stability of SH2 containing signaling proteins.
Ehm PAH et al.
Cellular Signalling, 2019
Compound Heterozygous Mutations of IL2-Inducible T cell Kinase in a Swedish Patient: the Importance of Early Genetic Diagnosis.
Fang M et al.
Journal of Clinical Immunology, 2019
Interleukin-2-Inducible T-Cell Kinase Deficiency-New Patients, New Insight?
Ghosh S et al.
Frontiers in Immunology, 2018
F-actin remodeling defects as revealed in primary immunodeficiency disorders.
Janssen WJ et al.
Clinical Immunology (orlando, Fla.), 2016
Interleukin-2-inducible T-cell kinase (ITK) deficiency - clinical and molecular aspects.
Ghosh S et al.
Journal of Clinical Immunology, 2014
Loss-of-function mutations within the IL-2 inducible kinase ITK in patients with EBV-associated lymphoproliferative diseases.
Linka RM et al.
Leukemia, 2012
Screening the PRF1, UNC13D, STX11, SH2D1A, XIAP, and ITK gene mutations in Chinese children with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis.
Zhizhuo H et al.
Pediatric Blood & Cancer, 2012
TEC family kinases in health and disease--loss-of-function of BTK and ITK and the gain-of-function fusions ITK-SYK and BTK-SYK.
Hussain A et al.
The Febs Journal, 2011
IL-2-inducible T-cell kinase deficiency: clinical presentation and therapeutic approach.
Stepensky P et al.
Haematologica, 2011
Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation.
Huck K et al.
The Journal of Clinical Investigation, 2009