Varaico: Literature-Extracted Genetic Variants

Gene:JAG1
Variant:p.D140A
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JAG1

NM_000214.3:p.D140A

Associated Papers

An N-glycan on the C2 domain of JAGGED1 is important for Notch activation.

Meng Y et al.

Science Signaling, 2022

Structural Insights into Notch Receptor-Ligand Interactions.

Handford PA et al.

Advances in Experimental Medicine and Biology, 2018

Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands.

Suckling RJ et al.

The Embo Journal, 2017

Structural analysis uncovers lipid-binding properties of Notch ligands.

Chillakuri CR et al.

Cell Reports, 2013

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