Associated Papers
Divergent molecular pathways drive monomorphic epitheliotropic and enteropathy-associated intestinal T-cell lymphoma.
Vallois D et al.
Leukemia, 2026
41057685 (PubMed )
Supplement: 41375_2025_2777_MOESM1_ESM.pdf
Clinical features, mutational landscape and their prognostic impact in Chinese paediatric patients with T-cell lymphoblastic lymphoma.
Li Y et al.
British Journal of Haematology, 2025
40958529 (PubMed )
Supplement: supplement_1.zip › Table_S3.xlsx › Sheet1
Mining cancer genomes for change-of-metabolic-function mutations.
Tu KJ et al.
Communications Biology, 2023
37950065 (PubMed )
Supplement: 42003_2023_5475_MOESM2_ESM.pdf
Structural Analysis of Janus Tyrosine Kinase Variants in Hematological Malignancies: Implications for Drug Development and Opportunities for Novel Therapeutic Strategies.
Rodriguez Moncivais OJ et al.
International Journal of Molecular Sciences, 2023
Base editing screens map mutations affecting interferon-γ signaling in cancer.
Coelho MA et al.
Cancer Cell, 2023
36669486 (PubMed )
Supplement: mmc4.xlsx › BE_variants_-clinical_relevance
Monomorphic epitheliotropic intestinal T-cell lymphoma comprises morphologic and genomic heterogeneity impacting outcome.
Veloza L et al.
Haematologica, 2023
35708139 (PubMed )
Supplement: 2022_281226_VELOZA_SUPPL.pdf
Identification of a novel functional JAK1 S646P mutation in acute lymphoblastic leukemia.
Li Q et al.
Oncotarget, 2017
Genomic characterization of pediatric T-cell acute lymphoblastic leukemia reveals novel recurrent driver mutations.
Spinella JF et al.
Oncotarget, 2016
27602765 (PubMed )
Supplement: oncotarget-07-65485-s004.xlsx › Sheet1
Hyperactivation of JAK1 tyrosine kinase induces stepwise, progressive pruritic dermatitis.
Yasuda T et al.
The Journal of Clinical Investigation, 2016
Genomic characterization of acute leukemias.
Chiaretti S et al.
Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre, 2014
JAK1 truncating mutations in gynecologic cancer define new role of cancer-associated protein tyrosine kinase aberrations.
Ren Y et al.
Scientific Reports, 2013
24154688 (PubMed )
Supplement: srep03042-s1.pdf
ALL-associated JAK1 mutations confer hypersensitivity to the antiproliferative effect of type I interferon.
Hornakova T et al.
Blood, 2010
Acute lymphoblastic leukemia-associated JAK1 mutants activate the Janus kinase/STAT pathway via interleukin-9 receptor alpha homodimers.
Hornakova T et al.
The Journal of Biological Chemistry, 2009
Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia.
Flex E et al.
The Journal of Experimental Medicine, 2008
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