Varaico: Literature-Extracted Genetic Variants

Gene:JAK1
Variant:p.S729C
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JAK1

NM_002227.4:p.S729C

Associated Papers

High-Frequency Mutations in TP53, AXIN1, CTNNB1, and KRAS, and Polymorphisms in JAK1 Genes Among Mongolian HCC Patients.

Bold N et al.

Cancer Reports (hoboken, N.j.), 2025

Whole-exome sequencing reveals genomic landscape of intrahepatic cholangiocarcinoma and identifies SAV1 as a potential driver.

Zhou ZJ et al.

Nature Communications, 2024

39551842 (PubMed )
Supplement: 41467_2024_54387_MOESM3_ESM.xlsx › Supplementary_Data_2

Study of sex-biased differences in genomic profiles in East Asian hepatocellular carcinoma.

Huang CY et al.

Discover Oncology, 2024

Deep whole-genome analysis of 494 hepatocellular carcinomas.

Chen L et al.

Nature, 2024

Somatic Evolution in Non-neoplastic IBD-Affected Colon.

Olafsson S et al.

Cell, 2020

32697969 (PubMed )
Supplement: mmc4.xlsx › A__TCGA_hotspots

The Mutational Features of Aristolochic Acid-Induced Mouse and Human Liver Cancers.

Lu ZN et al.

Hepatology (baltimore, Md.), 2020

Targeted sequencing reveals the mutational landscape responsible for sorafenib therapy in advanced hepatocellular carcinoma.

Tang J et al.

Theranostics, 2020

32373219 (PubMed )
Supplement: thnov10p5384s2.xlsx › S5-All_HCC_Mutations

Pharmacogenetics of hepatocellular carcinoma and cholangiocarcinoma.

Alonso-Peña M et al.

Cancer Drug Resistance (alhambra, Calif.), 2019

Activating JAK1 mutation may predict the sensitivity of JAK-STAT inhibition in hepatocellular carcinoma.

Yang S et al.

Oncotarget, 2016

Diverse modes of genomic alteration in hepatocellular carcinoma.

Jhunjhunwala S et al.

Genome Biology, 2014

25159915 (PubMed )
Supplement: 13059_2014_436_MOESM1_ESM.xlsx › Table_S2

Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma.

Kan Z et al.

Genome Research, 2013

Liver cancer oncogenomics: opportunities and dilemmas for clinical applications.

Marquardt JU et al.

Hepatic Oncology, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."