Varaico: Literature-Extracted Genetic Variants

Gene:JAK1
Variant:p.V658L
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JAK1

NM_002227.4:p.V658L

Associated Papers

Involvement of the JAK-STAT pathway in the molecular landscape of tyrosine kinase fusion-negative hypereosinophilic syndromes: A nationwide CEREO study.

Groh M et al.

American Journal of Hematology, 2024

GATA1 mutation analysis and molecular landscape characterization in acute myeloid leukemia with trisomy 21 in pediatric patients.

Panferova A et al.

International Journal of Laboratory Hematology, 2021

JAK1 somatic mutation in a myeloproliferative neoplasm.

Arulogun SO et al.

Haematologica, 2017

Regulation of JAK2 activation by Janus homology 2: evidence from molecular dynamics simulations.

Wan S et al.

Journal of Chemical Information and Modeling, 2012

Oncogenic JAK1 and JAK2-activating mutations resistant to ATP-competitive inhibitors.

Hornakova T et al.

Haematologica, 2011

Transforming JAK1 mutations exhibit differential signalling, FERM domain requirements and growth responses to interferon-γ.

Gordon GM et al.

The Biochemical Journal, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."