Associated Papers
Venetoclax durable response in adult relapsed/refractory Philadelphia-negative acute lymphoblastic leukemia with JAK/STAT pathway alterations.
Ferrari A et al.
Frontiers in Cell and Developmental Biology, 2023
Systemic Jak1 activation causes extrarenal calcitriol production and skeletal alterations provoking stunted growth.
Fuente R et al.
Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2021
Identification of a novel functional JAK1 S646P mutation in acute lymphoblastic leukemia.
Li Q et al.
Oncotarget, 2017
Cooperating JAK1 and JAK3 mutants increase resistance to JAK inhibitors.
Springuel L et al.
Blood, 2014
Transforming JAK1 mutations exhibit differential signalling, FERM domain requirements and growth responses to interferon-γ.
Gordon GM et al.
The Biochemical Journal, 2010
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