Varaico: Literature-Extracted Genetic Variants

Gene:JAK2
Variant:p.I559F
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JAK2

NM_004972.4:p.I559F

Associated Papers

Molecular basis of JAK2 activation in erythropoietin receptor and pathogenic JAK2 signaling.

Abraham BG et al.

Science Advances, 2024

Characterization of JAK1 Pseudokinase Domain in Cytokine Signaling.

Raivola J et al.

Cancers, 2019

Janus kinase 2 activation mechanisms revealed by analysis of suppressing mutations.

Hammarén HM et al.

The Journal of Allergy and Clinical Immunology, 2019

Hyperactivation of Oncogenic JAK3 Mutants Depend on ATP Binding to the Pseudokinase Domain.

Raivola J et al.

Frontiers in Oncology, 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."