Associated Papers
Next-generation sequencing redefines the diagnosis of triple-negative myeloproliferative neoplasms.
Wu S et al.
Annals of Hematology, 2022
Uncoupling JAK2 V617F activation from cytokine-induced signalling by modulation of JH2 αC helix.
Leroy E et al.
The Biochemical Journal, 2016
Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses.
Varghese LN et al.
The Biochemical Journal, 2014
The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling.
Ungureanu D et al.
Nature Structural & Molecular Biology, 2011
Polycythemia vera and its molecular basis: an update.
Chen G et al.
Best Practice & Research. Clinical Haematology, 2006
Role of tyrosine kinases and phosphatases in polycythemia vera.
Zhao ZJ et al.
Seminars in Hematology, 2005
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera.
James C et al.
Nature, 2005
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