Varaico: Literature-Extracted Genetic Variants

Gene:JAK2
Variant:p.S591L
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JAK2

NM_004972.4:p.S591L

Associated Papers

Structural Analysis of Janus Tyrosine Kinase Variants in Hematological Malignancies: Implications for Drug Development and Opportunities for Novel Therapeutic Strategies.

Rodriguez Moncivais OJ et al.

International Journal of Molecular Sciences, 2023

Genetic Background of Polycythemia Vera.

Regimbeau M et al.

Genes, 2022

Drug-sensitive FGFR3 mutations in lung adenocarcinoma.

Chandrani P et al.

Annals of Oncology : Official Journal of the European Society for Medical Oncology, 2017

27998968 (PubMed )
Supplement: mdw636_supp.zip › Chandrani_et_al._suppl_tables_20161110.xlsx › S3.Variants

Jak/STAT pathways in cytokine signaling and myeloproliferative disorders: approaches for targeted therapies.

Jatiani SS et al.

Genes & Cancer, 2010

A JAK2 interdomain linker relays Epo receptor engagement signals to kinase activation.

Zhao L et al.

The Journal of Biological Chemistry, 2009

Structural effects of clinically observed mutations in JAK2 exons 13-15: comparison with V617F and exon 12 mutations.

Lee TS et al.

Bmc Structural Biology, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."