Varaico: Literature-Extracted Genetic Variants

Gene:JAK2
Variant:p.E596K
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JAK2

NM_004972.4:p.E596K

Associated Papers

Base editing screens map mutations affecting interferon-γ signaling in cancer.

Coelho MA et al.

Cancer Cell, 2023

36669486 (PubMed )
Supplement: mmc4.xlsx › BE_variants_-clinical_relevance

Uncoupling JAK2 V617F activation from cytokine-induced signalling by modulation of JH2 αC helix.

Leroy E et al.

The Biochemical Journal, 2016

Polycythemia vera and its molecular basis: an update.

Chen G et al.

Best Practice & Research. Clinical Haematology, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."