Varaico: Literature-Extracted Genetic Variants

Gene:JAK3
Variant:p.Q865E
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JAK3

NM_000215.4:p.Q865E

Associated Papers

Evaluation of the genetic basis of familial-associated early-onset hematologic cancers in an ancestral/ethnically diverse population.

Feng Q et al.

Haematologica, 2024

38205536 (PubMed )
Supplement: 2023_284224_FENG_SUPPL_TABLES.xlsx › suppT4

Mutant JAK3 signaling is increased by loss of wild-type JAK3 or by acquisition of secondary JAK3 mutations in T-ALL.

Degryse S et al.

Blood, 2018

Targeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia.

Vicente C et al.

Haematologica, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."