Varaico: Literature-Extracted Genetic Variants

Gene:JAK3
Variant:p.T848A
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JAK3

NM_000215.4:p.T848A

Associated Papers

Loss of mutL homolog-1 (MLH1) expression promotes acquisition of oncogenic and inhibitor-resistant point mutations in tyrosine kinases.

Springuel L et al.

Cellular and Molecular Life Sciences : Cmls, 2016

Distinct Acute Lymphoblastic Leukemia (ALL)-associated Janus Kinase 3 (JAK3) Mutants Exhibit Different Cytokine-Receptor Requirements and JAK Inhibitor Specificities.

Losdyck E et al.

The Journal of Biological Chemistry, 2015

Cooperating JAK1 and JAK3 mutants increase resistance to JAK inhibitors.

Springuel L et al.

Blood, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."