Varaico: Literature-Extracted Genetic Variants

Gene:JAK3
Variant:p.L156P
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JAK3

NM_000215.4:p.L156P

Associated Papers

p.Y317H is a new JAK2 gain-of-function mutation affecting the FERM domain in a myelofibrosis patient with CALR mutation.

Eder-Azanza L et al.

Haematologica, 2017

Whole-genome sequencing reveals oncogenic mutations in mycosis fungoides.

McGirt LY et al.

Blood, 2015

JAK/STAT signaling in hematological malignancies.

Vainchenker W et al.

Oncogene, 2013

Janus kinase 3-activating mutations identified in natural killer/T-cell lymphoma.

Koo GC et al.

Cancer Discovery, 2012

FERM domain mutations induce gain of function in JAK3 in adult T-cell leukemia/lymphoma.

Elliott NE et al.

Blood, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."