Varaico: Literature-Extracted Genetic Variants

Gene:JMJD6
Variant:p.D189A
Back to variants list

JMJD6

NM_015167.3:p.D189A

Associated Papers

JMJD6 Dysfunction Due to Iron Deficiency in Preeclampsia Disrupts Fibronectin Homeostasis Resulting in Diminished Trophoblast Migration.

Alahari S et al.

Frontiers in Cell and Developmental Biology, 2021

JMJD6 participates in the maintenance of ribosomal DNA integrity in response to DNA damage.

Fages J et al.

Plos Genetics, 2020

JMJD6 modulates DNA damage response through downregulating H4K16ac independently of its enzymatic activity.

Huo D et al.

Cell Death and Differentiation, 2020

JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes.

Lee S et al.

Elife, 2020

Biochemical and structural investigations clarify the substrate selectivity of the 2-oxoglutarate oxygenase JMJD6.

Islam MS et al.

The Journal of Biological Chemistry, 2019

Faulty oxygen sensing disrupts angiomotin function in trophoblast cell migration and predisposes to preeclampsia.

Farrell A et al.

Jci Insight, 2019

Promotion of adipogenesis by JMJD6 requires the AT hook-like domain and is independent of its catalytic function.

Reyes-Gutierrez P et al.

Plos One, 2019

Compromised JMJD6 Histone Demethylase Activity Affects VHL Gene Repression in Preeclampsia.

Alahari S et al.

The Journal of Clinical Endocrinology and Metabolism, 2018

JMJD6 promotes melanoma carcinogenesis through regulation of the alternative splicing of PAK1, a key MAPK signaling component.

Liu X et al.

Molecular Cancer, 2017

Loading of PAX3 to Mitotic Chromosomes Is Mediated by Arginine Methylation and Associated with Waardenburg Syndrome.

Wu TF et al.

The Journal of Biological Chemistry, 2015

Role of JMJD6 in Breast Tumourigenesis.

Poulard C et al.

Plos One, 2015

Jumonji domain containing protein 6 (Jmjd6) modulates splicing and specifically interacts with arginine-serine-rich (RS) domains of SR- and SR-like proteins.

Heim A et al.

Nucleic Acids Research, 2014

JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation.

Wang F et al.

Plos Biology, 2014

The polyserine domain of the lysyl-5 hydroxylase Jmjd6 mediates subnuclear localization.

Wolf A et al.

The Biochemical Journal, 2013

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."