Varaico: Literature-Extracted Genetic Variants

Gene:JUN
Variant:p.S63A
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JUN

NM_002228.4:p.S63A

Associated Papers

A micropeptide JunBP regulated by TGF-β promotes hepatocellular carcinoma metastasis.

Zhang H et al.

Oncogene, 2023

An intrinsic temporal order of c-JUN N-terminal phosphorylation regulates its activity by orchestrating co-factor recruitment.

Waudby CA et al.

Nature Communications, 2022

AP-1 imprints a reversible transcriptional programme of senescent cells.

Martínez-Zamudio RI et al.

Nature Cell Biology, 2020

Cooperative regulation of mouse aldose reductase (AKR1B3) gene transcription by Nrf2, TonEBP, and c-jun.

Nishinaka T et al.

Chemico-biological Interactions, 2019

Nuclear Dvl, c-Jun, beta-catenin, and TCF form a complex leading to stabilization of beta-catenin-TCF interaction.

Gan XQ et al.

The Journal of Cell Biology, 2008

c-Jun promotes cellular survival by suppression of PTEN.

Hettinger K et al.

Cell Death and Differentiation, 2007

Functional dissection of the plant-specific SBP-domain: overlap of the DNA-binding and nuclear localization domains.

Birkenbihl RP et al.

Journal of Molecular Biology, 2005

Schnurri-3 (KRC) interacts with c-Jun to regulate the IL-2 gene in T cells.

Oukka M et al.

The Journal of Experimental Medicine, 2004

Contribution of the Atm protein to maintaining cellular homeostasis evidenced by continuous activation of the AP-1 pathway in Atm-deficient brains.

Weizman N et al.

The Journal of Biological Chemistry, 2003

c-Jun and p53 activity is modulated by SUMO-1 modification.

Muller S et al.

The Journal of Biological Chemistry, 2000

Inhibition of the Jun kinase pathway blocks DNA repair, enhances p53-mediated apoptosis and promotes gene amplification.

Gjerset RA et al.

Cell Growth & Differentiation : the Molecular Biology Journal of the American Association for Cancer Research, 1999

Role of the ATFa/JNK2 complex in Jun activation.

De Graeve F et al.

Oncogene, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."