Associated Papers
ACSS2 coupled with KAT7 regulates histone β-hydroxybutyrylation to enhance transcription.
Wang S et al.
Science Advances, 2025
40815653 (PubMed )
Supplement: sciadv.adv8448_sm.pdf
HBO1, a MYSTerious KAT and its links to cancer.
Yokoyama A et al.
Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms, 2024
HBO1 catalyzes lysine lactylation and mediates histone H3K9la to regulate gene transcription.
Niu Z et al.
Nature Communications, 2024
Lysine 2-hydroxyisobutyrylation of NAT10 promotes cancer metastasis in an ac4C-dependent manner.
Liao L et al.
Cell Research, 2023
HBO1 is a versatile histone acyltransferase critical for promoter histone acylations.
Xiao Y et al.
Nucleic Acids Research, 2021
KAT7 is a genetic vulnerability of acute myeloid leukemias driven by MLL rearrangements.
Au YZ et al.
Leukemia, 2021
HBO1 is required for the maintenance of leukaemia stem cells.
MacPherson L et al.
Nature, 2020
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