Varaico: Literature-Extracted Genetic Variants

Gene:KAT8
Variant:p.E350Q
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KAT8

NM_032188.3:p.E350Q

Associated Papers

Stabilization of MOF (KAT8) by USP10 promotes esophageal squamous cell carcinoma proliferation and metastasis through epigenetic activation of ANXA2/Wnt signaling.

Li P et al.

Oncogene, 2024

COX17 acetylation via MOF-KANSL complex promotes mitochondrial integrity and function.

Guhathakurta S et al.

Nature Metabolism, 2023

Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis.

Radzisheuskaya A et al.

Molecular Cell, 2021

Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature.

Sheikh BN et al.

Nature Cell Biology, 2020

MOF as an evolutionarily conserved histone crotonyltransferase and transcriptional activation by histone acetyltransferase-deficient and crotonyltransferase-competent CBP/p300.

Liu X et al.

Cell Discovery, 2017

Structural and Functional Role of Acetyltransferase hMOF K274 Autoacetylation.

McCullough CE et al.

The Journal of Biological Chemistry, 2016

Autoacetylation of the MYST lysine acetyltransferase MOF protein.

Yang C et al.

The Journal of Biological Chemistry, 2012

MYST protein acetyltransferase activity requires active site lysine autoacetylation.

Yuan H et al.

The Embo Journal, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."