Varaico: Literature-Extracted Genetic Variants

Gene:KBTBD4
Variant:p.I50T
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KBTBD4

NM_018095.6:p.I50T

Associated Papers

Structural mimicry of UM171 and neomorphic cancer mutants co-opts E3 ligase KBTBD4 for HDAC1/2 recruitment.

Chen Z et al.

Nature Communications, 2025

UM171 glues asymmetric CRL3-HDAC1/2 assembly to degrade CoREST corepressors.

Yeo MJR et al.

Nature, 2025

39939761 (PubMed )
Supplement: NIHMS2059347-supplement-Supplementary_Data_11.xlsx › Supplementary_Data_11
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