Varaico: Literature-Extracted Genetic Variants

Gene:KCNA3
Variant:p.V369I
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KCNA3

NM_002232.5:p.V369I

Associated Papers

The Closed State of the Shaker Potassium Channel and the Mechanism of Voltage Activation.

Agrawal R et al.

Biorxiv : the Preprint Server for Biology, 2025

Resin-acid derivatives bind to multiple sites on the voltage-sensor domain of the Shaker potassium channel.

Silverå Ejneby M et al.

The Journal of General Physiology, 2021

A Common Kinetic Property of Mutations Linked to Episodic Ataxia Type 1 Studied in the Shaker Kv Channel.

Zhao J et al.

International Journal of Molecular Sciences, 2020

A single charged voltage sensor is capable of gating the Shaker K+ channel.

Gagnon DG et al.

The Journal of General Physiology, 2009

The cooperative voltage sensor motion that gates a potassium channel.

Pathak M et al.

The Journal of General Physiology, 2005

Mutations in the S4 region isolate the final voltage-dependent cooperative step in potassium channel activation.

Ledwell JL et al.

The Journal of General Physiology, 1999

Uncharged S4 residues and cooperativity in voltage-dependent potassium channel activation.

Smith-Maxwell CJ et al.

The Journal of General Physiology, 1998

Histidine substitution identifies a surface position and confers Cs+ selectivity on a K+ pore.

De Biasi M et al.

Biophysical Journal, 1993

A single nonpolar residue in the deep pore of related K+ channels acts as a K+:Rb+ conductance switch.

Kirsch GE et al.

Biophysical Journal, 1992

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."