Associated Papers
High-throughput screens identify genotype-specific therapeutics for channelopathies.
Egly CL et al.
Jci Insight, 2025
Structures Illuminate Cardiac Ion Channel Functions in Health and in Long QT Syndrome.
Brewer KR et al.
Frontiers in Pharmacology, 2020
Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanism.
Anderson CL et al.
Circulation, 2006
Requirement of negative residues, Asp 95 and Asp 105, in S2 on membrane integration of a voltage-dependent K+ channel, KAT1.
Sato Y et al.
Bioscience, Biotechnology, and Biochemistry, 2003
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