Associated Papers
Predicting the Damaging Potential of Uncharacterized KCNQ1 and KCNE1 Variants.
Tarnovskaya SI et al.
International Journal of Molecular Sciences, 2025
Computational analysis of congenital heart disease associated SNPs: unveiling their impact on the gene regulatory system.
Vashisht S et al.
Bmc Genomics, 2025
Genetic Atrial Cardiomyopathies: Common Features, Specific Differences, and Broader Relevance to Understanding Atrial Cardiomyopathy.
Marcoux E et al.
Circulation. Arrhythmia and Electrophysiology, 2023
Heritable arrhythmias associated with abnormal function of cardiac potassium channels.
Crotti L et al.
Cardiovascular Research, 2020
Genotype influence in responses to therapy for atrial fibrillation.
Huang H et al.
Expert Review of Cardiovascular Therapy, 2016
KCNA5 gene polymorphism associate with idiopathic atrial fibrillation.
Tian L et al.
International Journal of Clinical and Experimental Medicine, 2015
The role of the cytosolic HSP70 chaperone system in diseases caused by misfolding and aberrant trafficking of ion channels.
Young JC
Disease Models & Mechanisms, 2014
Role of genetic polymorphisms of ion channels in the pathophysiology of coronary microvascular dysfunction and ischemic heart disease.
Fedele F et al.
Basic Research in Cardiology, 2013
Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip.
Gaunt TR et al.
Circulation. Cardiovascular Genetics, 2012
Phenotypic manifestations of mutations in genes encoding subunits of cardiac potassium channels.
Shimizu W et al.
Circulation Research, 2011
Monogenic atrial fibrillation as pathophysiological paradigms.
Mahida S et al.
Cardiovascular Research, 2011
[Readthrough of nonsense mutation W822X in the SCN5A gene can effectively restore expression of cardiac Na+ channels W822X].
Zhang JT et al.
Zhonghua Xin Xue Guan Bing Za Zhi, 2011
Emerging concepts in the pharmacogenomics of arrhythmias: ion channel trafficking.
Harkcom WT et al.
Expert Review of Cardiovascular Therapy, 2010
[Identification and functional analysis of a KCNA5 mutation responsible for idiopathic atrial fibrillation].
Yang YQ et al.
Zhonghua Yi Xue Za Zhi, 2010
Readthrough of nonsense mutation W822X in the SCN5A gene can effectively restore expression of cardiac Na+ channels.
Teng S et al.
Cardiovascular Research, 2009
Novel KCNA5 loss-of-function mutations responsible for atrial fibrillation.
Yang Y et al.
Journal of Human Genetics, 2009
Aminoglycoside antibiotics restore functional expression of truncated HERG channels produced by nonsense mutations.
Yao Y et al.
Heart Rhythm, 2009
Introducing sense into nonsense in treatments of human genetic diseases.
Linde L et al.
Trends in Genetics : Tig, 2008
The non-synonymous coding IKr-channel variant KCNH2-K897T is associated with atrial fibrillation: results from a systematic candidate gene-based analysis of KCNH2 (HERG).
Sinner MF et al.
European Heart Journal, 2008
A pilot study to estimate the feasibility of assessing the relationships between polymorphisms in hKv1.5 and atrial fibrillation in patients following coronary artery bypass graft surgery.
Plante I et al.
The Canadian Journal of Cardiology, 2008
Atrial fibrillation--a new cardiac channelopathy.
Otway R et al.
Heart, Lung & Circulation, 2007
Aminoglycoside-induced translational read-through in disease: overcoming nonsense mutations by pharmacogenetic therapy.
Zingman LV et al.
Clinical Pharmacology and Therapeutics, 2007
Kv1.5 channelopathy due to KCNA5 loss-of-function mutation causes human atrial fibrillation.
Olson TM et al.
Human Molecular Genetics, 2006