Varaico: Literature-Extracted Genetic Variants

Gene:KCNA5
Variant:p.H463R
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KCNA5

NM_002234.4:p.H463R

Associated Papers

Computational Studies Show How the H463R Mutation Turns hKv1.5 into an Inactivation State.

Rahman RA et al.

The Journal of Physical Chemistry. B, 2024

Functional Characterization of Rare Variants Implicated in Susceptibility to Lone Atrial Fibrillation.

Hayashi K et al.

Circulation. Arrhythmia and Electrophysiology, 2015

ShakerIR and Kv1.5 mutant channels with enhanced slow inactivation also exhibit K⁺ o-dependent resting inactivation.

Cheng YM et al.

Pflugers Archiv : European Journal of Physiology, 2013

SCAM analysis reveals a discrete region of the pore turret that modulates slow inactivation in Kv1.5.

Eduljee C et al.

American Journal of Physiology. Cell Physiology, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."