Varaico: Literature-Extracted Genetic Variants

Gene:KCNA5
Variant:p.T479A
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KCNA5

NM_002234.4:p.T479A

Associated Papers

Open channel block of Kv1.5 channels by HMQ1611.

Dong C et al.

Frontiers in Pharmacology, 2022

Identification of Verapamil Binding Sites Within Human Kv1.5 Channel Using Mutagenesis and Docking Simulation.

Ding WG et al.

Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology, 2019

Interactions of Propofol With Human Voltage-gated Kv1.5 Channel Determined by Docking Simulation and Mutagenesis Analyses.

Kojima A et al.

Journal of Cardiovascular Pharmacology, 2018

Regulation of human cardiac Kv1.5 channels by extracellular acidification.

Wang S et al.

Pflugers Archiv : European Journal of Physiology, 2016

Putative binding sites for arachidonic acid on the human cardiac Kv 1.5 channel.

Bai JY et al.

British Journal of Pharmacology, 2015

The molecular basis of high-affinity binding of the antiarrhythmic compound vernakalant (RSD1235) to Kv1.5 channels.

Eldstrom J et al.

Molecular Pharmacology, 2007

Structural basis for competition between drug binding and Kvbeta 1.3 accessory subunit-induced N-type inactivation of Kv1.5 channels.

Decher N et al.

Molecular Pharmacology, 2005

Molecular basis for Kv1.5 channel block: conservation of drug binding sites among voltage-gated K+ channels.

Decher N et al.

The Journal of Biological Chemistry, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."