Associated Papers
Selectivity filter mutations shift ion permeation mechanism in potassium channels.
Mironenko A et al.
Pnas Nexus, 2024
Open channel block of Kv1.5 channels by HMQ1611.
Dong C et al.
Frontiers in Pharmacology, 2022
The Selectivity Filter Is Involved in the U-Type Inactivation Process of Kv2.1 and Kv3.1 Channels.
Coonen L et al.
Biophysical Journal, 2020
Identification of Verapamil Binding Sites Within Human Kv1.5 Channel Using Mutagenesis and Docking Simulation.
Ding WG et al.
Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology, 2019
Interactions of Propofol With Human Voltage-gated Kv1.5 Channel Determined by Docking Simulation and Mutagenesis Analyses.
Kojima A et al.
Journal of Cardiovascular Pharmacology, 2018
Regulation of human cardiac Kv1.5 channels by extracellular acidification.
Wang S et al.
Pflugers Archiv : European Journal of Physiology, 2016
Putative binding sites for arachidonic acid on the human cardiac Kv 1.5 channel.
Bai JY et al.
British Journal of Pharmacology, 2015
Interaction of propofol with voltage-gated human Kv1.5 channel through specific amino acids within the pore region.
Kojima A et al.
European Journal of Pharmacology, 2015
High-throughput analysis of drug binding interactions for the human cardiac channel, Kv1.5.
Karczewski J et al.
Biochemical Pharmacology, 2009
Inhibitory actions of the phosphatidylinositol 3-kinase inhibitor LY294002 on the human Kv1.5 channel.
Wu J et al.
British Journal of Pharmacology, 2009
Cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate and nordihydroguaiaretic acid inhibit human Kv1.5 currents independently of lipoxygenase.
Gong YZ et al.
European Journal of Pharmacology, 2008
Structural determinants of Kvbeta1.3-induced channel inactivation: a hairpin modulated by PIP2.
Decher N et al.
The Embo Journal, 2008
The molecular basis of high-affinity binding of the antiarrhythmic compound vernakalant (RSD1235) to Kv1.5 channels.
Eldstrom J et al.
Molecular Pharmacology, 2007
Structural basis for competition between drug binding and Kvbeta 1.3 accessory subunit-induced N-type inactivation of Kv1.5 channels.
Decher N et al.
Molecular Pharmacology, 2005
Molecular basis for Kv1.5 channel block: conservation of drug binding sites among voltage-gated K+ channels.
Decher N et al.
The Journal of Biological Chemistry, 2004