Varaico: Literature-Extracted Genetic Variants

Gene:KCNA5
Variant:p.V505A
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KCNA5

NM_002234.4:p.V505A

Associated Papers

Predicting the Damaging Potential of Uncharacterized KCNQ1 and KCNE1 Variants.

Tarnovskaya SI et al.

International Journal of Molecular Sciences, 2025

40724807 (PubMed )
Supplement: ijms-26-06561-s001.zip › ijms-3705358_SupplementaryTable1.xlsx › SupplementaryTable1_upd

Open channel block of Kv1.5 channels by HMQ1611.

Dong C et al.

Frontiers in Pharmacology, 2022

Identification of Verapamil Binding Sites Within Human Kv1.5 Channel Using Mutagenesis and Docking Simulation.

Ding WG et al.

Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology, 2019

Interactions of Propofol With Human Voltage-gated Kv1.5 Channel Determined by Docking Simulation and Mutagenesis Analyses.

Kojima A et al.

Journal of Cardiovascular Pharmacology, 2018

Regulation of human cardiac Kv1.5 channels by extracellular acidification.

Wang S et al.

Pflugers Archiv : European Journal of Physiology, 2016

High-throughput analysis of drug binding interactions for the human cardiac channel, Kv1.5.

Karczewski J et al.

Biochemical Pharmacology, 2009

The molecular basis of high-affinity binding of the antiarrhythmic compound vernakalant (RSD1235) to Kv1.5 channels.

Eldstrom J et al.

Molecular Pharmacology, 2007

Structural basis for competition between drug binding and Kvbeta 1.3 accessory subunit-induced N-type inactivation of Kv1.5 channels.

Decher N et al.

Molecular Pharmacology, 2005

Molecular basis for Kv1.5 channel block: conservation of drug binding sites among voltage-gated K+ channels.

Decher N et al.

The Journal of Biological Chemistry, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."