Varaico: Literature-Extracted Genetic Variants

Gene:KCNE1
Variant:p.G55C
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KCNE1

NM_000219.6:p.G55C

Associated Papers

High-throughput functional mapping of variants in an arrhythmia gene, KCNE1, reveals novel biology.

Muhammad A et al.

Genome Medicine, 2024

38816749 (PubMed )
Supplement: 13073_2024_1340_MOESM3_ESM.xlsx › SpliceAI

Pharmacological rescue of specific long QT variants of KCNQ1/KCNE1 channels.

Zou X et al.

Frontiers in Physiology, 2022

Allosteric mechanism for KCNE1 modulation of KCNQ1 potassium channel activation.

Kuenze G et al.

Elife, 2020

33095155 (PubMed )
Supplement: elife-57680-fig7-data1.xlsx › Panel_C_-_Q1_activation_Vhalf

Probing Structural Dynamics and Topology of the KCNE1 Membrane Protein in Lipid Bilayers via Site-Directed Spin Labeling and Electron Paramagnetic Resonance Spectroscopy.

Sahu ID et al.

Biochemistry, 2015

Structural investigation of the transmembrane domain of KCNE1 in proteoliposomes.

Sahu ID et al.

Biochemistry, 2014

Regulation of Voltage-Activated K(+) Channel Gating by Transmembrane β Subunits.

Sun X et al.

Frontiers in Pharmacology, 2012

KCNQ1 subdomains involved in KCNE modulation revealed by an invertebrate KCNQ1 orthologue.

Nakajo K et al.

The Journal of General Physiology, 2011

The MinK-related peptides.

McCrossan ZA et al.

Neuropharmacology, 2004

TEA(+)-sensitive KCNQ1 constructs reveal pore-independent access to KCNE1 in assembled I(Ks) channels.

Kurokawa J et al.

The Journal of General Physiology, 2001

MinK subdomains that mediate modulation of and association with KvLQT1.

Tapper AR et al.

The Journal of General Physiology, 2000

MinK endows the I(Ks) potassium channel pore with sensitivity to internal tetraethylammonium.

Sesti F et al.

Biophysical Journal, 2000

Single-channel characteristics of wild-type IKs channels and channels formed with two minK mutants that cause long QT syndrome.

Sesti F et al.

The Journal of General Physiology, 1998

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