Associated Papers
High-throughput functional mapping of variants in an arrhythmia gene, KCNE1, reveals novel biology.
Muhammad A et al.
Genome Medicine, 2024
38816749 (PubMed )
Supplement: 13073_2024_1340_MOESM3_ESM.xlsx › SpliceAI
Allosteric mechanism for KCNE1 modulation of KCNQ1 potassium channel activation.
Kuenze G et al.
Elife, 2020
33095155 (PubMed )
Supplement: elife-57680-fig7-data1.xlsx › Panel_C_-_Q1_activation_Vhalf
Probing Structural Dynamics and Topology of the KCNE1 Membrane Protein in Lipid Bilayers via Site-Directed Spin Labeling and Electron Paramagnetic Resonance Spectroscopy.
Sahu ID et al.
Biochemistry, 2015
Probing the structural basis for differential KCNQ1 modulation by KCNE1 and KCNE2.
Wang Y et al.
The Journal of General Physiology, 2012
Reconstitution of KCNE1 into lipid bilayers: comparing the structural, dynamic, and activity differences in micelle and vesicle environments.
Coey AT et al.
Biochemistry, 2011
KCNQ1 subdomains involved in KCNE modulation revealed by an invertebrate KCNQ1 orthologue.
Nakajo K et al.
The Journal of General Physiology, 2011
KCNE regulation of KvLQT1 channels: structure-function correlates.
Melman YF et al.
Trends in Cardiovascular Medicine, 2002
Potassium channel subunits encoded by the KCNE gene family: physiology and pathophysiology of the MinK-related peptides (MiRPs).
Abbott GW et al.
Molecular Interventions, 2001
TEA(+)-sensitive KCNQ1 constructs reveal pore-independent access to KCNE1 in assembled I(Ks) channels.
Kurokawa J et al.
The Journal of General Physiology, 2001
MinK endows the I(Ks) potassium channel pore with sensitivity to internal tetraethylammonium.
Sesti F et al.
Biophysical Journal, 2000
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