Associated Papers
Dynamic protein-protein interactions of KCNQ1 and KCNE1 measured by EPR line shape analysis.
Stowe RB et al.
Biochimica Et Biophysica Acta. Biomembranes, 2024
High-throughput functional mapping of variants in an arrhythmia gene, KCNE1, reveals novel biology.
Muhammad A et al.
Genome Medicine, 2024
38816749 (PubMed )
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Delayed KCNQ1/KCNE1 assembly on the cell surface helps IKs fulfil its function as a repolarization reserve in the heart.
Wilson ZT et al.
The Journal of Physiology, 2021
Insights into Cardiac IKs (KCNQ1/KCNE1) Channels Regulation.
Wu X et al.
International Journal of Molecular Sciences, 2020
The I Ks Ion Channel Activator Mefenamic Acid Requires KCNE1 and Modulates Channel Gating in a Subunit-Dependent Manner.
Wang Y et al.
Molecular Pharmacology, 2020
KCNE1 tunes the sensitivity of KV7.1 to polyunsaturated fatty acids by moving turret residues close to the binding site.
Larsson JE et al.
Elife, 2018
Building KCNQ1/KCNE1 channel models and probing their interactions by molecular-dynamics simulations.
Xu Y et al.
Biophysical Journal, 2013
Probing the structural basis for differential KCNQ1 modulation by KCNE1 and KCNE2.
Wang Y et al.
The Journal of General Physiology, 2012
Characterization of KCNQ1 atrial fibrillation mutations reveals distinct dependence on KCNE1.
Chan PJ et al.
The Journal of General Physiology, 2012
Gating-related molecular motions in the extracellular domain of the IKs channel: implications for IKs channelopathy.
Wang YH et al.
The Journal of Membrane Biology, 2011
KCNQ1 and KCNE1 in the IKs channel complex make state-dependent contacts in their extracellular domains.
Xu X et al.
The Journal of General Physiology, 2008
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