Varaico: Literature-Extracted Genetic Variants

Gene:KCNH2
Variant:p.I647F
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KCNH2

NM_000238.4:p.I647F

Associated Papers

Dissociation of E-4031 from the HERG channel caused by mutations of an amino acid results in greater block at high stimulation frequency.

Ishii K et al.

Cardiovascular Research, 2003

An amino acid residue whose change by mutation affects drug binding to the HERG channel.

Ishii K et al.

Febs Letters, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."