Varaico: Literature-Extracted Genetic Variants

Gene:KCNH2
Variant:p.S641C
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KCNH2

NM_000238.4:p.S641C

Associated Papers

Molecular determinants of human ether-à-go-go-related gene 1 (hERG1) K+ channel activation by NS1643.

Grunnet M et al.

Molecular Pharmacology, 2011

PD-118057 contacts the pore helix of hERG1 channels to attenuate inactivation and enhance K+ conductance.

Perry M et al.

Proceedings of the National Academy of Sciences of the United States of America, 2009

S641 contributes HERG K+ channel inactivation.

Bian JS et al.

Cell Biochemistry and Biophysics, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."