Associated Papers
Inhibition of the hERG Potassium Channel by a Methanesulphonate-Free E-4031 Analogue.
Helliwell MV et al.
Pharmaceuticals (basel, Switzerland), 2023
Identification of a novel pathogenic variant in KCNH2 in an Iranian family with long QT syndrome 2 by whole-exome sequencing.
Fazelifar AF et al.
Journal of Arrhythmia, 2023
Structural modeling of the hERG potassium channel and associated drug interactions.
Maly J et al.
Frontiers in Pharmacology, 2022
Investigating the state dependence of drug binding in hERG channels using a trapped-open channel phenotype.
Thouta S et al.
Scientific Reports, 2018
Ubiquitination-dependent quality control of hERG K+ channel with acquired and inherited conformational defect at the plasma membrane.
Apaja PM et al.
Molecular Biology of the Cell, 2013
Molecular determinants of pentamidine-induced hERG trafficking inhibition.
Dennis AT et al.
Molecular Pharmacology, 2012
Extracellular K+ is a prerequisite for the function and plasma membrane stability of HERG channels.
Massaeli H et al.
Circulation Research, 2010
Intracellular potassium stabilizes human ether-à-go-go-related gene channels for export from endoplasmic reticulum.
Wang L et al.
Molecular Pharmacology, 2009
Na+ permeation and block of hERG potassium channels.
Gang H et al.
The Journal of General Physiology, 2006
Molecular determinants of cocaine block of human ether-á-go-go-related gene potassium channels.
Guo J et al.
The Journal of Pharmacology and Experimental Therapeutics, 2006
Molecular determinants for high-affinity block of human EAG potassium channels by antiarrhythmic agents.
Gessner G et al.
Molecular Pharmacology, 2004
S641 contributes HERG K+ channel inactivation.
Bian JS et al.
Cell Biochemistry and Biophysics, 2004
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