Varaico: Literature-Extracted Genetic Variants

Gene:KCNH2
Variant:p.S631Y
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KCNH2

NM_000238.4:p.S631Y

Associated Papers

Mapping the sequence of conformational changes underlying selectivity filter gating in the K(v)11.1 potassium channel.

Wang DT et al.

Nature Structural & Molecular Biology, 2011

Mapping the binding site of a human ether-a-go-go-related gene-specific peptide toxin (ErgTx) to the channel's outer vestibule.

Pardo-Lopez L et al.

The Journal of Biological Chemistry, 2002

Use-dependent 'agonist' effect of azimilide on the HERG channel.

Jiang M et al.

The Journal of Pharmacology and Experimental Therapeutics, 1999

Effects of outer mouth mutations on hERG channel function: a comparison with similar mutations in the Shaker channel.

Fan JS et al.

Biophysical Journal, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."