Varaico: Literature-Extracted Genetic Variants

Gene:KCNH2
Variant:p.S620C
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KCNH2

NM_000238.4:p.S620C

Associated Papers

Impacts of gene variants on drug effects-the foundation of genotype-guided pharmacologic therapy for long QT syndrome and short QT syndrome.

Zhao Z et al.

Ebiomedicine, 2024

Blockade of the Human Ether A-Go-Go-Related Gene (hERG) Potassium Channel by Fentanyl.

Tschirhart JN et al.

Molecular Pharmacology, 2019

The Link between Inactivation and High-Affinity Block of hERG1 Channels.

Wu W et al.

Molecular Pharmacology, 2015

Current pharmacogenomic studies on hERG potassium channels.

He FZ et al.

Trends in Molecular Medicine, 2013

Blockade of the human ether-a-go-go-related gene potassium channel by ketanserin.

Tu DN et al.

Sheng Li Xue Bao : [acta Physiologica Sinica], 2008

Molecular determinants of cocaine block of human ether-á-go-go-related gene potassium channels.

Guo J et al.

The Journal of Pharmacology and Experimental Therapeutics, 2006

S641 contributes HERG K+ channel inactivation.

Bian JS et al.

Cell Biochemistry and Biophysics, 2004

Molecular determinants of inactivation and dofetilide block in ether a-go-go (EAG) channels and EAG-related K(+) channels.

Ficker E et al.

Molecular Pharmacology, 2001

Molecular determinants of dofetilide block of HERG K+ channels.

Ficker E et al.

Circulation Research, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."