Varaico: Literature-Extracted Genetic Variants

Gene:KCNH2
Variant:p.V549A
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KCNH2

NM_000238.4:p.V549A

Associated Papers

Tyrosine Residues from the S4-S5 Linker of Kv11.1 Channels Are Critical for Slow Deactivation.

Ng CA et al.

The Journal of Biological Chemistry, 2016

The S4-S5 linker acts as a signal integrator for HERG K+ channel activation and deactivation gating.

Ng CA et al.

Plos One, 2012

Molecular determinants of human ether-à-go-go-related gene 1 (hERG1) K+ channel activation by NS1643.

Grunnet M et al.

Molecular Pharmacology, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."