Associated Papers
A need for exhaustive and standardized characterization of ion channels activity. The case of KV11.1.
Alameh M et al.
Frontiers in Physiology, 2023
36860515 (PubMed )
Supplement: Table1.XLSX › missense_variants
Structures Illuminate Cardiac Ion Channel Functions in Health and in Long QT Syndrome.
Brewer KR et al.
Frontiers in Pharmacology, 2020
32431610 (PubMed )
Supplement: Table_1.xlsx › mutation_list
Tyrosine Residues from the S4-S5 Linker of Kv11.1 Channels Are Critical for Slow Deactivation.
Ng CA et al.
The Journal of Biological Chemistry, 2016
Molecular determinants of pentamidine-induced hERG trafficking inhibition.
Dennis AT et al.
Molecular Pharmacology, 2012
The S4-S5 linker acts as a signal integrator for HERG K+ channel activation and deactivation gating.
Ng CA et al.
Plos One, 2012
A plethora of mechanisms in the HERG-related long QT syndrome. Genetics meets electrophysiology.
Roden DM et al.
Cardiovascular Research, 1999
Mutations of the S4-S5 linker alter activation properties of HERG potassium channels expressed in Xenopus oocytes.
Sanguinetti MC et al.
The Journal of Physiology, 1999
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