Varaico: Literature-Extracted Genetic Variants

Gene:KCNH2
Variant:p.Y542C
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KCNH2

NM_000238.4:p.Y542C

Associated Papers

Molecular Determinants of Voltage-Dependent Gating in Kv11.1 Channels.

Hunter DV et al.

Advances in Experimental Medicine and Biology, 2026

C-Linker Accounts for Differential Sensitivity of ERG1 and ERG2 K+ Channels to RPR260243-Induced Slow Deactivation.

Gardner A et al.

Molecular Pharmacology, 2015

Getting to the heart of hERG K(+) channel gating.

Perry MD et al.

The Journal of Physiology, 2015

Mapping of interactions between the N- and C-termini and the channel core in HERG K+ channels.

de la Peña P et al.

The Biochemical Journal, 2013

hERG K(+) channels: structure, function, and clinical significance.

Vandenberg JI et al.

Physiological Reviews, 2012

Molecular determinants of interactions between the N-terminal domain and the transmembrane core that modulate hERG K+ channel gating.

Fernández-Trillo J et al.

Plos One, 2011

Participation of HERG channel cytoplasmic structures on regulation by the G protein-coupled TRH receptor.

Alonso-Ron C et al.

Pflugers Archiv : European Journal of Physiology, 2009

Thermodynamic and kinetic properties of amino-terminal and S4-S5 loop HERG channel mutants under steady-state conditions.

Alonso-Ron C et al.

Biophysical Journal, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."