Associated Papers
The Fast Component of hERG Gating Charge: An Interaction between D411 in the S1 and S4 Residues.
Dou Y et al.
Biophysical Journal, 2017
Tyrosine Residues from the S4-S5 Linker of Kv11.1 Channels Are Critical for Slow Deactivation.
Ng CA et al.
The Journal of Biological Chemistry, 2016
The S4-S5 linker acts as a signal integrator for HERG K+ channel activation and deactivation gating.
Ng CA et al.
Plos One, 2012
The low-potency, voltage-dependent HERG blocker propafenone--molecular determinants and drug trapping.
Witchel HJ et al.
Molecular Pharmacology, 2004
Functional interaction between extracellular sodium, potassium and inactivation gating in HERG channels.
Mullins FM et al.
The Journal of Physiology, 2004
Trapping of a methanesulfonanilide by closure of the HERG potassium channel activation gate.
Mitcheson JS et al.
The Journal of General Physiology, 2000
A plethora of mechanisms in the HERG-related long QT syndrome. Genetics meets electrophysiology.
Roden DM et al.
Cardiovascular Research, 1999
Mutations of the S4-S5 linker alter activation properties of HERG potassium channels expressed in Xenopus oocytes.
Sanguinetti MC et al.
The Journal of Physiology, 1999
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