Varaico: Literature-Extracted Genetic Variants

Gene:KCNH2
Variant:p.V535A
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KCNH2

NM_000238.4:p.V535A

Associated Papers

Population-specific variations in KCNH2 predispose patients to delayed ventricular repolarization upon dihydroartemisinin-piperaquine therapy.

Camara MD et al.

Antimicrobial Agents and Chemotherapy, 2024

The Fast Component of hERG Gating Charge: An Interaction between D411 in the S1 and S4 Residues.

Dou Y et al.

Biophysical Journal, 2017

Tyrosine Residues from the S4-S5 Linker of Kv11.1 Channels Are Critical for Slow Deactivation.

Ng CA et al.

The Journal of Biological Chemistry, 2016

Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels.

Perry MD et al.

The Journal of General Physiology, 2013

Cloning and functional characterization of the smooth muscle ether-a-go-go-related gene K+ channel. Potential role of a conserved amino acid substitution in the S4 region.

Shoeb F et al.

The Journal of Biological Chemistry, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."