Varaico: Literature-Extracted Genetic Variants

Gene:KCNH2
Variant:p.A453S
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KCNH2

NM_000238.4:p.A453S

Associated Papers

hERG K(+) channels: structure, function, and clinical significance.

Vandenberg JI et al.

Physiological Reviews, 2012

Structural determinants of potassium channel blockade and drug-induced arrhythmias.

Wehrens XH

Handbook of Experimental Pharmacology, 2006

Molecular determinants for high-affinity block of human EAG potassium channels by antiarrhythmic agents.

Gessner G et al.

Molecular Pharmacology, 2004

S641 contributes HERG K+ channel inactivation.

Bian JS et al.

Cell Biochemistry and Biophysics, 2004

Molecular determinants of inactivation and dofetilide block in ether a-go-go (EAG) channels and EAG-related K(+) channels.

Ficker E et al.

Molecular Pharmacology, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."