Associated Papers
High-throughput screens identify genotype-specific therapeutics for channelopathies.
Egly CL et al.
Jci Insight, 2025
41026531 (PubMed )
Supplement: jciinsight-10-191697-s190.xlsx › Figure_6B
The neutral, hydrophobic isoleucine at position I521 in the extracellular S4 domain of hERG contributes to channel gating equilibrium.
Dou Y et al.
American Journal of Physiology. Cell Physiology, 2013
Movement of the S4 segment in the hERG potassium channel during membrane depolarization.
Elliott DJ et al.
Molecular Membrane Biology, 2009
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